Genetic analysis of bacteriophage T4 lysozyme structure and function

Experimental studies with T4 lysozyme and various other proteins reveal the importance of genetic techniques in the investigation of structure-activity relationship of enzymes. Genetic techniques help determine the correlation between amino acid sequence and protein structure and understand the enzyme's catalytic mechanisms. Application of site-directed mutagenesis to examine the hypothesis derived from considering the protein's structure is a powerful and efficient method.