Ginsenosides compound (shen-fu) attenuates gastrointestinal injury and inhibits inflammatory response after cardiopulmonary bypass in patients with congenital heart disease

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jtcvs.2005.02.046 Byline: Zhong-yuan Xia (a)(b), Xian-Yi Liu (a)(b), Li-ying Zhan (a)(b), Yi-hong He (a), Tao Luo (a)(b), Zhengyuan Xia (a)(b) Abstract: This study was undertaken to demonstrate that gastrointestinal mucosal injury occurs during cardiopulmonary bypass in children, increasing systemic inflammatory responses, and to determine whether shen-fu injection (the major components of which are ginsenosides compound, extract of Panax ginseng shown to have antioxidant properties) could attenuate gastrointestinal mucosal injury and subsequent inflammatory responses. Author Affiliation: (a) Anesthesiology Research Laboratory, Renmin Hospital, Wuhan University, Wuhan, People's Republic of China (b) Department of Anesthesiology, Renmin Hospital, Wuhan University, Wuhan, People's Republic of China Article History: Received 21 November 2004; Revised 26 January 2005; Accepted 7 February 2005