Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs)

Authors :: Peyssonnaux, Carole
Zinkernagel, Annelies S.
Schuepbach, Reto A.
Rankin, Erinn
Vaulont, Sophie
Haase, Volker H.
Nizet, Victor
Johnson, Randall S.
Source :: Journal of Clinical Investigation. July, 2007, Vol. 117 Issue 7, p1926, 7 p.
Publication Year :: 2007
Abstract: Iron is essential for many biological processes, including oxygen delivery, and its supply is tightly regulated. Hepcidin, a small peptide synthesized in the liver, is a key regulator of iron [...]

Subjects :: Homeostasis -- Research
Iron in the body -- Physiological aspects
Hypoxia -- Research
DNA binding proteins -- Physiological aspects

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