Muscle-specific knockout of PKC-[lambda] impairs glucose transport and induces metabolic and diabetic syndromes

Authors :: Farese, Robert V.
Sajan, Mini P.
Yang, Hong
Li, Pengfei
Mastorides, Steven
Gower Jr., William R.
Nimal, Sonali
Choi, Cheol Soo
Kim, Sheene
Shulman, Gerald I.
Kahn, C. Ronald
Braun, Ursula
Leitges, Michae
Source :: Journal of Clinical Investigation. August, 2007, Vol. 117 Issue 8, p2289, 13 p.
Publication Year :: 2007
Abstract: Obesity, the metabolic syndrome, and type 2 diabetes mellitus (T2DM) are major global health problems. Insulin resistance is frequently present in these disorders, but the causes and effects of such [...]

Subjects :: Diabetes -- Risk factors
Diabetes -- Research
Metabolic syndrome X -- Risk factors
Metabolic syndrome X -- Research
Protein kinases -- Health aspects
Protein kinases -- Physiological aspects
Protein kinases -- Research

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