AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

Authors :: Claret, Marc
Smith, Mark A.
Batterham, Rachel L.
Selman, Colin
Choudhury, Agharul I.
Fryer, Lee G.D.
Clements, Melanie
Qassab, Hind Al
Heffron, Helen
Xu, Allison W.
Speakman, John R.
Barsh, Gregory S.
Viollet, Benoit
Vaulont, Sophie
Ashford, Michael L.J.
David Carling
Withers, Dominic J.
Source :: Journal of Clinical Investigation. August, 2007, Vol. 117 Issue 8, p2325, 12 p.
Publication Year :: 2007
Abstract: Hypothalamic AMP-activated protein kinase (AMPK) has been suggested to act as a key sensing mechanism, responding to hormones and nutrients in the regulation of energy homeostasis. However, the precise neuronal [...]

Subjects :: Cyclic adenylic acid -- Research
Protein kinases -- Research
Homeostasis -- Research
Cellular control mechanisms -- Research

Tools