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Ten-year results of a comparison of conservation with mastectomy in the treatment of stage I and II breast cancer

Authors :
Jacobson, Joan A.
Danforth, David N.
Cowen, Kenneth H.
D'Angelo, Teresa
Steinberg, Seth M.
Pierce, Lori
Lippman, Marc E.
Lichter, Allen S.
Glatstein, Eli
Okunieff, Paul
Source :
The New England Journal of Medicine. April 6, 1995, Vol. v332 Issue n14, p907, 5 p.
Publication Year :
1995

Abstract

A lumpectomy followed by radiation treatment may be just as effective in treating breast cancer as a mastectomy. A lumpectomy is a method of removing the tumor while preserving most of the breast. Of 237 women with breast cancer followed by the National Cancer Institute, 116 had received a mastectomy and 121 had a lumpectomy plus radiation. Ten-year survival rates were 77% in the lumpectomy group and 75% in the mastectomy group. Seventy-two percent of the women in the lumpectomy group were in remission at 10 years, compared to 69% of those in the mastectomy group. Eighteen patients in the lumpectomy group had a recurrence of cancer in the breast and were successfully treated with a mastectomy. Fifteen were disease-free three months to 10 years after the mastectomy. In both groups, women with smaller tumors and no spread of cancer to the lymph nodes had better survival rates.

Details

ISSN :
00284793
Volume :
v332
Issue :
n14
Database :
Gale General OneFile
Journal :
The New England Journal of Medicine
Publication Type :
Academic Journal
Accession number :
edsgcl.16799012