Abrogation of macrophage migration inhibitory factor decreases West Nile virus lethality by limiting viral neuroinvasion

Authors :: Arjona, Alvaro
Foellmer, Harald G.
Town, Terrence
Leng, Lin
McDonald, Courtney
Wang, Tian
Susan J. Wong
Montgomery, Ruth R.
Fikrig, Erol
Bucala, Richard
Source :: Journal of Clinical Investigation. Oct, 2007, Vol. 117 Issue 10, p3059, 8 p.
Publication Year :: 2007
Abstract: The flavivirus West Nile virus (WNV) is an emerging pathogen that causes life-threatening encephalitis in susceptible individuals. We investigated the role of the proinflammatory cytokine macrophage migration inhibitory factor (MIF), [...]

Subjects :: West Nile virus -- Complications and side effects
West Nile virus -- Research
Encephalitis -- Risk factors
Encephalitis -- Care and treatment
Encephalitis -- Research
Peptide regulatory factors -- Complications and side effects
Peptide regulatory factors -- Research

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