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Strategies for the culture of CHO-S cells

Authors :
Auton, Kevin A.
Bick, Julie A.
Taylor, Ian M.
Source :
Genetic Engineering and Biotechnology News. Sept 15, 2007, Vol. 27 Issue 16, p42, 2 p.
Publication Year :
2007

Abstract

The application of simple-batch and fed-batch growth strategies for the culture of CHO-S cells using Cellexus Biosystem's CellMaker PLUS bioreactor with disposable HybridBag is presented. Results show that the simple-batch culture showed comparable growth curves with a concentration of 4.1 x10(super 6) cells/mL, but is limiting to larger volumes. Fed-batch culture meanwhile exhibited a 3.8 x10(super 6) cells/mL concentration.

Details

Language :
English
ISSN :
1935472X
Volume :
27
Issue :
16
Database :
Gale General OneFile
Journal :
Genetic Engineering and Biotechnology News
Publication Type :
Periodical
Accession number :
edsgcl.171567373