Enantioselective intramolecular cyclopropanations of allylic and homoallylic diazoacetates amd diazoacetamides using chiral dirhodium(II) carboxamide catalysts

Authors :: Doyle, Michael P.
Austin, Richard E.
Bailey, A. Scott
Dwyer, Michael P.
Dyatkin, Alexey B.
Kalinin, Alexey V.
Kwan, Michelle M.Y.
Liras, Spiros
Oalmann, Christopher J.
Pieters, Roland J.
Protopopova, Marina N.
Raab, Conrad E.
Roos, Gregory H.P.
Zhou, Qi-Lin
Martin, Stephen F.
Source :: Journal of the American Chemical Society. May 31, 1995, Vol. 117 Issue 21, p5763, 13 p.
Publication Year :: 1995
Abstract: The feasibility of using chiral dirhodium(II) tetrakis(methyl 2-pyrrolidone-5 S-carboxylate), Rh2(5S-MEPY)4 and its enantiomer, Rh2(5R-MEPY)4, as catalysts for the intramolecular cyclopropanations of allylic and homoallylic diazoacetates and diazoacetamides was evaluated. Results showed that the use of the chiral dirhodium(II) catalysts produced cyclopropanes with excellent enantioselectivity.

Subjects :: Decomposition (Chemistry) -- Research
Catalysts -- Analysis
Chemistry

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