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Prevalence of pathogenic BRCA1 mutation carriers in 5 US racial/ethnic groups

Authors :
John, Esther M.
Miron, Alexander
Gong, Gail
Phipps, Amanda I.
Felberg, Anna
Li, Frederick P.
West, Dee W.
Whittemore, Alice S.
Source :
JAMA, The Journal of the American Medical Association. Dec 26, 2007, Vol. 298 Issue 24, p2869, 8 p.
Publication Year :
2007

Abstract

A study to compare the extent Hispanics, African Americans and Asian Americans as carriers of the tumor suppressor gene BRCA1 compared to white non-Hispanics with and without Ashkenazi Jewish ancestry is conducted. Results reveal that the mutated gene was highest in Hispanics and Asian Americans displayed the lowest.

Subjects

Subjects :
African Americans -- Health aspects
African Americans -- Genetic aspects
Asian Americans -- Health aspects
Asian Americans -- Genetic aspects
Hispanic Americans -- Health aspects
Hispanic Americans -- Genetic aspects
Tumor suppressor genes -- Research

Details

Language :
English
ISSN :
00987484
Volume :
298
Issue :
24
Database :
Gale General OneFile
Journal :
JAMA, The Journal of the American Medical Association
Publication Type :
Academic Journal
Accession number :
edsgcl.173359057

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