The biosynthesis of spinosyn in Saccharopolyspora spinosa: synthesis of the cross-bridging precursor and identification of the function of SpnJ

Authors :: Hak Joong Kim
Rongson Pongdee
Qingquan Wu
Lin Hong
Hung-wen Liu
Source :: Journal of the American Chemical Society. Nov 28, 2007, Vol. 129 Issue 47, 14582-14584
Publication Year :: 2007
Abstract: The biosynthesis of spinosyn macrolides in Saccharopolyspora spinosa is discussed. The analysis reveals that these macrolides act as the cross-linking precursors with SpnJ acting as the catalyst.

Subjects :: Macrolide antibiotics -- Chemical properties
Polyketides -- Chemical properties
Ring formation (Chemistry) -- Analysis
Chemistry

Tools