Facile synthesis of a 'ready to use' precursor of porphobilinogen and its amino acid derivatives

Authors :: Soldermann, Carole Pissot
Vallinayagam, Ramakrishnan
Tzouros, Manuel
Neier, Reinhard
Source :: Journal of Organic Chemistry. Jan 18, 2008, Vol. 73 Issue 2, p764, 4 p.
Publication Year :: 2008
Abstract: An efficient synthesis of porphobilinogen by employing Mukaiyama aldol reaction between the regioselectively formed silyl enol ether and the acetal of methyl 5-azidolevulinate is reported.

Subjects :: Pyrrole -- Research
Pyrrole -- Chemical properties
Porphyrins -- Research
Porphyrins -- Physiological aspects
Porphyrins -- Chemical properties
Biological sciences
Chemistry

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