Microarray-formatted clinical biomarker assay development using peptide aptamers to anterior gradient-2

Authors :: Murray, Euan
McKenna, Ekaterina O.
Burch, Lindsay R.
Dillon, John
Langridge-Smith, Pat
Kolch, Walter
Pitt, Andrew
Hupp, Ted R.
Source :: Biochemistry. Dec 4, 2007, Vol. 46 Issue 48, 13742-13751
Publication Year :: 2007
Abstract: A proteomic technological approach to characterize anterior gradient-2 protein as p53 inhibitor which is over expressed in human cancer is described. The method could be applied to develop clinical biomarker assay in an aptamer microarray format.

Subjects :: Mutagenesis -- Analysis
Cellular proteins -- Structure
Cellular proteins -- Health aspects
Proteolysis -- Analysis
Cancer -- Care and treatment
Biological sciences
Chemistry

Tools