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Metrics of sequence constraint overlook regulatory sequences in an exhaustive analysis at phox2b
- Source :
- Genome Research. Feb, 2008, Vol. 18 Issue 2, 252-260
- Publication Year :
- 2008
-
Abstract
- A study is conducted on zebrafish phox2b locus, employing a transgenic enhancer assay in zebrafish to determine the regulatory activity of 48 amplions tiled across 40.7-kb interval encompassing this gene. Results showed that the established algorithms detected only 29%-61% of the identified regulatory elements.
Details
- Language :
- English
- ISSN :
- 10889051
- Volume :
- 18
- Issue :
- 2
- Database :
- Gale General OneFile
- Journal :
- Genome Research
- Publication Type :
- Periodical
- Accession number :
- edsgcl.175920075