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A synthesis of 6-azabicyclo[3.2.1]octanes. The role of N-substitution
- Source :
- Journal of Organic Chemistry. Feb 15, 2008, Vol. 73 Issue 4, 1462-1467
- Publication Year :
- 2008
-
Abstract
- A new synthesis method is described for the aziridine required for the aziridine-[pi]-nucleophile cyclization for preparing 6-azabicyclo[3.2.1]octanes. The studies have shown that N-diphenylphospinyl and N-H aziridines have not led to the desired bicyclic ring systems, whereas a nosyl group on the aziridine nitrogen has led to the bicyclic ring system.
Details
- Language :
- English
- ISSN :
- 00223263
- Volume :
- 73
- Issue :
- 4
- Database :
- Gale General OneFile
- Journal :
- Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.176765208