Tandem Michael addition/ylide epoxidation for the synthesis of highly functionalized cyclohexadiene epoxide derivatives

Authors :: Qing-Gang Wang
Xian-Ming Deng
Ben-Hu Zhu
Long-Wu Ye
Xiu-Li Sun
Chuan-Ying Li
Chun-Yin Zhu
Qi Shen
Yong Tang
Source :: Journal of the American Chemical Society. April 23, 2008, Vol. 130 Issue 16, 5408-5409
Publication Year :: 2008
Abstract: A tandem Michael addition/ylide epoxidation is developed for the rapid creation of highly functionalized cyclohexadiene epoxide skeletons with three stereocenters. The readily accessible starting material, mild reaction conditions, high selectivities and recoverable chiral sulfide has made this reaction very useful in organic synthesis.

Subjects :: Nuclear magnetic resonance spectroscopy -- Analysis
Ylides -- Structure
Ylides -- Chemical properties
Ylides -- Spectra
Organic compounds -- Synthesis
Organic compounds -- Analysis
Alkadienes -- Structure
Alkadienes -- Chemical properties
Alkadienes -- Spectra
Chemistry

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