Asymmetric synthesis of (-)-incarvillateine employing an intramolecular alkylation via Rh-catalyzed olefinic C-H bond activation

Authors :: Tsai, Andy S.
Bergman, Robert G.
Ellman, Jonathan A.
Source :: Journal of the American Chemical Society. May 21, 2008, Vol. 130 Issue 20, 6316-6317
Publication Year :: 2008
Abstract: A new approach using an intramolecular alkylation of an olefinic C-H bond catalyzed by Rh for the asymmetric synthesis of (-)-incarvillateine is discussed. The method is shown to be extremely stable and high-yielding.

Subjects :: Olefins -- Chemical properties
Alkylation -- Analysis
Catalysis -- Analysis
Chemical bonds -- Analysis
Rhodium -- Chemical properties
Chemistry

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