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Coding potential of the X region of human T-cell leukemia/lymphotropic virus type II
- Source :
- Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. Sept 15, 1996, Vol. 13 Issue SUPP1, pS220, 8 p.
- Publication Year :
- 1996
-
Abstract
- Differences in proteins produced by certain gene sequences could explain the different diseases caused by human T-cell leukemia/lymphotropic viruses I and II (HTLV-I and HTLV-II). The viruses have similar genes and both can cause T cells to turn cancerous. However, HTLV-II has not been conclusively linked to any disease yet, unlike HTLV-I, which has been linked to adult T cell leukemia and a muscle disease. Analysis of the X region of the viral genes reveals that each virus produces different proteins. Research has shown that mutations in the X region can produce a less virulent virus.
Details
- ISSN :
- 10779450
- Volume :
- 13
- Issue :
- SUPP1
- Database :
- Gale General OneFile
- Journal :
- Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
- Publication Type :
- Periodical
- Accession number :
- edsgcl.18730222