Active site-directed double mutants of dihydrofolate reductase

Authors :: Ercikanabali, E.A.
Mineishi, S.
Tong, Y.Z.
Nakahara, S.
Waltham, M.C.
Banerjee, D.
Chen, W.
Sadelain, M.
Bertino, J.R.
Source :: Cancer Weekly Plus. October 21, 1996, p29, 2 p.
Publication Year :: 1996
Abstract: According to the authors' abstract of an article published in Cancer Research, 'Variants of dihydrofolate reductase (DHFR), which confer resistance to antifolates, are used as dominant selectable markers in vitro [...]