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μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence

Authors :
Bohn, Laura M.
Gainetdinov, Raul R.
Lin, Fang-Tsyr
Lefkowitz, Robert J.
Caron, Marc G.
Source :
Nature. December 7, 2000, Vol. 408 Issue 6813, p720, 4 p.
Publication Year :
2000

Abstract

Author(s): Laura M. Bohn [1]; Raul R. Gainetdinov [1]; Fang-Tsyr Lin [2]; Robert J. Lefkowitz [2]; Marc G. Caron (corresponding author) [1] Morphine is a powerful pain reliever, but also [...]

Details

Language :
English
ISSN :
00280836
Volume :
408
Issue :
6813
Database :
Gale General OneFile
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
edsgcl.188051363
Full Text :
https://doi.org/10.1038/35047086