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E2F1 represses β-catenin transcription and is antagonized by both pRB and CDK8
- Source :
- Nature. September 25, 2008, Vol. 455 Issue 7212, p552, 7 p.
- Publication Year :
- 2008
-
Abstract
- The E2F1 transcription factor can promote proliferation or apoptosis when activated, and is a key downstream target of the retinoblastoma tumour suppressor protein (pRB). Here we show that E2F1 is [...]
- Subjects :
- DNA-ligand interactions -- Research -- Health aspects -- Chemical properties -- Physiological aspects
Apoptosis -- Causes of -- Research -- Physiological aspects -- Health aspects -- Chemical properties
Genetic transcription -- Evaluation -- Research -- Health aspects -- Chemical properties -- Physiological aspects
DNA binding proteins -- Physiological aspects -- Chemical properties -- Health aspects -- Research
Environmental issues
Science and technology
Zoology and wildlife conservation
Evaluation
Physiological aspects
Chemical properties
Research
Health aspects
Causes of
Subjects
Details
- Language :
- English
- ISSN :
- 00280836
- Volume :
- 455
- Issue :
- 7212
- Database :
- Gale General OneFile
- Journal :
- Nature
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.188847582