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Selective cytotoxic Ru(II) arene Cp* complex salts [[R-PhRuCp*].sup.+][X.sup.-] for X =: B[F.sub.4.sup.-], P[F.sub.6.sup.-], and B[Ph.sub.4.sup.-]
Selective cytotoxic Ru(II) arene Cp* complex salts [[R-PhRuCp*].sup.+][X.sup.-] for X =: B[F.sub.4.sup.-], P[F.sub.6.sup.-], and B[Ph.sub.4.sup.-]
- Source :
- Inorganic Chemistry. Oct 6, 2008, Vol. 47 Issue 19, 8589-8591
- Publication Year :
- 2008
-
Abstract
- The article describes the synthesis and characterization of a series of ionic Ru(II) arene Cp* sandwich complexes. The results from screening for cytotoxicity against a range of human tumor cell lines and normal human cells reveal the complexes to exhibit promising anticancer activity that varies with changes in the arene ligand and the anionic counterion.
Details
- Language :
- English
- ISSN :
- 00201669
- Volume :
- 47
- Issue :
- 19
- Database :
- Gale General OneFile
- Journal :
- Inorganic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.189768776