Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin

Authors :: Roll-Mecak, Antonina
Vale, Ronald D.
Source :: Nature. January 17, 2008, Vol. 451 Issue 7176, p363, 5 p.
Publication Year :: 2008
Abstract: Author(s): Antonina Roll-Mecak [1]; Ronald D. Vale (corresponding author) [1] Spastin, the most common locus for mutations in hereditary spastic paraplegias [1], and katanin are related microtubule-severing AAA ATPases [2, [...]

Subjects :: Research
Genetic aspects
Health aspects
Gene mutation -- Health aspects -- Research -- Genetic aspects
Microtubules -- Health aspects -- Genetic aspects -- Research
Paraplegia -- Genetic aspects -- Research
Gene mutations -- Health aspects -- Research -- Genetic aspects

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