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Post-transcriptional processing generates a diversity of 5'-modified long and short RNAs

Authors :
Fejes-Toth, Katalin
Sotirova, Vihra
Sachidanandam, Ravi
Assaf, Gordon
Hannon, Gregory J.
Kapranov, Philipp
Foissac, Sylvain
Willingham, Aarron T.
Duttagupta, Radha
Dumais, Erica
Gingeras, Thomas R.
Source :
Nature. February 19, 2009, Vol. 457 Issue 7232, p1028, 5 p.
Publication Year :
2009

Abstract

Affymetrix/Cold Spring Harbor Laboratory ENCODE Transcriptome Project * The repertoire of RNAs found in eukaryotic cells is unexpectedly complex, with virtually the entire non-repeat portions of many genomes being transcribed [...]<br />The transcriptomes of eukaryotic cells are incredibly complex. Individual non-coding RNAs dwarf the number of protein-coding genes, and include classes that are well understood as well as classes for which the nature, extent and functional roles are obscure (1). Deep sequencing of small RNAs (

Details

Language :
English
ISSN :
00280836
Volume :
457
Issue :
7232
Database :
Gale General OneFile
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
edsgcl.194697814