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Viral decoy vetoes killer cell

Authors :
Karre, Klas
Welsh, Raymond M.
Source :
Nature. April 3, 1997, Vol. 386 Issue 6624, p446, 2 p.
Publication Year :
1997

Abstract

Viruses avoid destruction by T cells through masking their presence by not expressing major histocompatibility complex (MHC) molecules. However, natural killer (NK) cells destroy any cells that do not express MHC molecules. Some viruses, including cytomegalovirus, have been found to evade detection and destruction by natural killer (NK) cells as well by adopting a decoy approach and expressing a homologue of normal MHC molecules.

Details

ISSN :
00280836
Volume :
386
Issue :
6624
Database :
Gale General OneFile
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
edsgcl.19636069