Distribution and clearance of orally consumed lead in lactating cows

Authors :: Blanford, J.J.
Willet, L.B.
Becker, C.J.
Bromund, R.H.
Source :: Toxic Substance Mechanisms. April-June, 1997, Vol. 16 Issue 2, p93, 13 p.
Publication Year :: 1997
Abstract: Study results fail to clearly demonstrate chelation therapy's effectiveness and safety in removing lead from cattle. An experiment using five lactating Holstein cows that were administered meso-2,3-dimercaptosuccinic acid and monoisoamyl meso-2,3-dimercaptosuccinate demonstrated that 0.3 mg/kg doses of those chelators were inadequate to cause large amounts of lead excretion through urine.