Carotid baroreflex control of heart rate during acute exposure to simulated altitudes of 3,800 m and 4,300 m

A study was conducted on the baroreflex response in humans during acute high-altitude exposure. A neck chamber was employed in seven unacclimatized male subjects to plot R-R intervals while a four-parameter sigmoidal logistic function was used to analyze the baroreceptor response. The findings indicate that hypoxia reduces the sensitivity of carotid baroreflex cardiac response.