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Genetic variants associated with cardiac structure and function

Authors :
Vasan, Ramachandran S.
Glazer, Nicole L.
Felix, Janine F.
Lieb, Wolfgang
Wild, Philipp S.
Felix, Stephan B
Watzinger, Norbert
Larson, Martin G.
Smith, Nicholas L.
Dehghan, Abbas
Gro-henning, Anika
Schillert, Arne
Teumer, Alexander
Schmidt, Reinhold
Kathiresan, Sekar
Lumley, Thomas
Aulchenko, Yurii S.
Konig, Inke R.
Zeller, Tanja
Homuth, Georg
Struchalin, Maksim
Aragam, Jayashri
Bis, Joshua C.
Rivadeneira, Fernando
Erdmann, Jeanette
Schnabel, Renate B.
Dorr, Marcus
Zweiker, Robert
Lind Lars
Rodeheffer, Richard J.
Greiser, Karin Halina
Levy, Daniel
Haritunians, Talin
Deckers, Jaap W.
Stritzke, Jan
Lackner, Karl J.
Volker, Uwe
Ingelsson, Erik
Kullo, Iftikhar
Haerting, Johannes
OEDonnell, Christopher J.
Heckbert, Susan R.
Stricker, Bruno H.
Ziegler, Andreas
Reffelmann, Thorsten
Redfield, Margaret M.
Werdan, Karl
Mitchell, Gary F.
Rice, Kenneth
Arnett, Donna K.
Hofman, Albert
Gottdiener, John S.
Uitterlinden, Andre G.
Meitinger, Thomas
Blettner, Maria
Friedrich, Nele
Wang, Thomas J.
Psaty, Bruce M.
van Duijn, Cornelia M.
Wichmann, H.-Erich
Munzel, Thomas F.
Kroemer, Heyo K.
Benjamin, Emelia J.
Rotter, Jerome I.
Witteman, Jacqueline C.
Schunkert, Heribert
Schmidt, Helena
Volzke, Henry
Blankenberg, Stefan
Source :
JAMA, The Journal of the American Medical Association. July 8, 2009, Vol. 302 Issue 2, p168, 11 p.
Publication Year :
2009

Abstract

A study was conducted to investigate and identify genetic variants that are associated with cardiac structure and function through a meta-analysis. Results indicated that there were 5 genetic loci, associated with variance in cardiac dimensions and aortic root size; however, the proportion of variance is quite small.

Details

Language :
English
ISSN :
00987484
Volume :
302
Issue :
2
Database :
Gale General OneFile
Journal :
JAMA, The Journal of the American Medical Association
Publication Type :
Academic Journal
Accession number :
edsgcl.204469385