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UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans
- Source :
- Cell. March 20, 1998, Vol. 92 Issue 6, p785, 11 p.
- Publication Year :
- 1998
-
Abstract
- Research was conducted to characterize the unc-73 gene product from Caenorhabditis elegans as it relates to guided cell and growth cone migrations. Results showed that unc-73 affected several cell migrations in C. elegans and influenced pioneer and non-pioneer growth cone and cell migrations. They also indicated that the unc-73 peptide was capable of activating Rac and inducing actin reorganization characteristic of membrane ruffling.
Details
- ISSN :
- 00928674
- Volume :
- 92
- Issue :
- 6
- Database :
- Gale General OneFile
- Journal :
- Cell
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.20635195