A cobalt(III) chiroporphyrin and its amine adducts. A potential chiral NMR shift reagent for amines

A study was conducted on the chlorocobalt(III) complex of alphaBetaalphaBeta-tetramethylchiroporphyrin, CoCl(TMCP), as a potential enantioselective host or chiral NMR shift reagent for optically active amines. The findings indicate that CoCl(TMCP) may be act as a chiral NMR shift reagent for conformational studies of chiral amines and as an analytical reagent for determining their enantiomer composition.