Failure of treatment with first-line Lopinavir boosted with Ritonavir can be explained by novel resistance pathways with protease mutation 76V

Authors :: Nijhuis, Monique
Wensing, Annemarie M.J.
Bierman, Wouter F.W.
de Jong, Dorien
Kagan, Ron
Fun, Axel
Jaspers, Christian A.J.J.
Schurink, Karin A.M.
van Agtmael, Michael A.
Boucher, Charles A.B.
Source :: Journal of Infectious Diseases. Sept 1, 2009, Vol. 200 Issue 5, p698, 12 p.
Publication Year :: 2009

Subjects :: Gene mutations -- Research
Gene mutations -- Physiological aspects
Ritonavir -- Dosage and administration
Ritonavir -- Health aspects
Proteases -- Research
Proteases -- Physiological aspects
Drug resistance -- Research
HIV (Viruses) -- Drug therapy
Health

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