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The p51 subunit of human immunodeficiency virus type 1 reverse transcriptase is essential in loading the p66 subunit on the template primer
The p51 subunit of human immunodeficiency virus type 1 reverse transcriptase is essential in loading the p66 subunit on the template primer
- Source :
- Biochemistry. April 28, 1998, Vol. 37 Issue 17, p5903, 6 p.
- Publication Year :
- 1998
-
Abstract
- A study was conducted to examine the possible function of the p51 subunit of HIV-1 reverse transcriptase (RT) in the template-primer binding process. The effects of acetonitrile addition on the polymerase activity of HIV-1 RT were also studied before and after the templaten primer binding step. Results indicated that acetonitrile dissociated the subunits of the HIV-1 RT into catalytically inactive monomers.
Details
- ISSN :
- 00062960
- Volume :
- 37
- Issue :
- 17
- Database :
- Gale General OneFile
- Journal :
- Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.21010359