Coronary heart disease in moderately hypercholesterolemic, hypertensive black and non-black patients randomized to pravastatin versus usual care: The Antihypertensive and Lipid Lowering to Prevent Heart Attack Trial (ALLHAT-LLT)

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ahj.2009.10.001 Byline: Karen L. Margolis (a), Kay Dunn (b), Lara M. Simpson (b), Charles E. Ford (b), Jeff D. Williamson (c), David J. Gordon (d), Paula T. Einhorn (d), Jeffrey L. Probstfield (e) Abstract: In previous analyses in ALLHAT, blacks had a significantly lower risk of coronary heart disease (CHD) in the pravastatin group compared to the usual care group, whereas non-blacks had no benefit from pravastatin. No previous statin trial has reported results separately in blacks. Author Affiliation: (a) HealthPartners Research Foundation, Minneapolis, MN (b) Coordinating Center for Clinical Trials, University of Texas-Houston Health Science Center School of Public Health, Houston, TX (c) J Paul Sticht Center on Aging, Bowman Gray School of Medicine, Winston-Salem, NC (d) Division of Prevention and Population Sciences and Division of Cardiovascular Diseases, National Heart, Lung, and Blood Institute, Bethesda, MD (e) Division of Cardiology, University of Washington School of Medicine, Seattle, WA Article History: Received 30 April 2009; Accepted 5 October 2009