A candidate gene analysis of methylphenidate response in attention-deficit/hyperactivity disorder

Authors :: McGough, James J.
McCrackenm, James T.
Loo, Sandra K.
Manganiello, Marc
Leung, Michael C.
Tietjens, Jeremy R.
Trinh, Thao
Baweja, Shilpa
Suddath, Robert
Smalley, Susan L.
Hellemann, Gerhard
Sugar, Catherine A.
Source :: Journal of the American Academy of Child and Adolescent Psychiatry. Dec, 2009, Vol. 48 Issue 12, p1155, 10 p.
Publication Year :: 2009
Abstract: Methylphenidate response in the treatment of attention-deficit/hyperactivity disorder (ADHD) was predicted by polymorphism at the serotonin transporter (SLCC6A4) intron 2 VNTR (p=.01). This confirms previous studies that suggest a moderating effect of genes on ADHD treatment response.

Subjects :: Methylphenidate -- Dosage and administration
Methylphenidate hydrochloride -- Dosage and administration
Pharmacogenetics -- Analysis
Attention-deficit hyperactivity disorder -- Drug therapy
Attention-deficit hyperactivity disorder -- Genetic aspects
Family and marriage
Psychology and mental health

Language :: English
ISSN :: 08908567
Volume :: 48
Issue :: 12
Database :: Gale General OneFile
Journal :: Journal of the American Academy of Child and Adolescent Psychiatry
Publication Type :: Academic Journal
Accession number :: edsgcl.214427984

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