Variants of DENND1B associated with asthma in children

Authors :: Sleiman, Patrick M.A.
Flory, James
Imielinski, Marcin
Bradfield, Jonathan P.
Annaiah, Kiran
Willis-Owen, Saffron A.G.
Kai Wang
Rafaels, Nicholas M.
Michel, Sven
Bonnelykke, Klaus
Haitao Zhang
Kim, Cecilia E.
Frackelton, Edward C.
Glessner, Joseph T.
Cuiping Hou
Otieno, F. George
Santa, Erin
Thomas, Kelly
Smith, Ryan M.
Glaberson, Wendy R.
Garris, Maria
Chiavacci, Rosetta M.
Beaty, Terri H.
Ruczinski, Ingo
Orange, Jordan M.
Allen, Julian
Spergel, Jonathan M.
Grundmeier, Robert
Mathias, Rasika A.
Christie, Jason D.
von Mutius, Erika
Cookson, WIlliam O.C.
Kabesch, Michael
Moffatt, Miriam F.
Grunstein, Michael M.
Barnes, Kathleen C.
Devoto, Marcella
Magnusson, Mark
Hongzhe Li
Grant, Struan F.A.
Bisgaard, Hans
Hakonarson, Hakon
Source :: The New England Journal of Medicine. Dec 31, 2009, Vol. 361 Issue 27, p36, 8 p.
Publication Year :: 2009
Abstract: A study was conducted to evaluate whether variants of DENND1B locus may influence the onset of asthma in children. Results have indicated that the locus DENND1B is associated with susceptibility to asthma.

Subjects :: Asthma in children -- Genetic aspects
Corticosteroids -- Usage
Single nucleotide polymorphisms -- Analysis

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