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Control of muscle differentiation by a mitochondria-targeted fluorophore
- Source :
- Journal of the American Chemical Society. Jan 20, 2010, Vol. 132 Issue 2, 576-579
- Publication Year :
- 2010
-
Abstract
- A mitochondria-targeted rosamine library in C2C12 myogenesis was applied to identify the compound that regulates the muscle differentiation during the remarkable changes undergone by mitochondria. The findings from the study provide insight into the potential application of fluorescent small molecules in the discovery of a bioactive probe that induces a specific cellular response.
Details
- Language :
- English
- ISSN :
- 00027863
- Volume :
- 132
- Issue :
- 2
- Database :
- Gale General OneFile
- Journal :
- Journal of the American Chemical Society
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.217640887