Green tea extract inhibits proliferation of uterine leiomyoma cells in vitro and in nude mice

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ajog.2009.10.885 Byline: Dong Zhang, Mohamed Al-Hendy, Gloria Richard-Davis, Valerie Montgomery-Rice, Chakradhari Sharan, Veera Rajaratnam, Anjali Khurana, Ayman Al-Hendy Keywords: apoptosis; epigallocatechin gallate (EGCG); green tea extract; inhibitory effect; uterine leiomyoma Abstract: The purpose of this study was to investigate the effect of epigallocatechin gallate (EGCG) on rat leiomyoma (ELT3) cells in vitro and in a nude mice model. Author Affiliation: Center for Women's Health Research, Department of Obstetrics and Gynecology, Meharry Medical College, Nashville, TN Article History: Received 31 March 2009; Revised 31 August 2009; Accepted 28 October 2009 Article Note: (footnote) This study was supported by Research Center for Minority Institutes (RCMI) Grant G12 RR03032 and National Institutes of Health/National Institute of Child Health and Human Development 1 R01 HD046228 (A.A.)., Cite this article as: Zhang D, Al-Hendy M, Richard-Davis G, et al. Green tea extract inhibits proliferation of uterine leiomyoma cells in vitro and in nude mice. Am J Obstet Gynecol 2010;202:289.e1-9.