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Genome-wide linkage scan reveals three putative breast-cancer-susceptibility loci

Authors :
Rosa-Rosa, Juan Manuel
Pita, Guillermo
Urioste, Miguel
Llort, Gemma
Brunet, Joan
Blanco, Ignacio
Cajal, Ramon y.
de la Hoya, Miguel
Caldes, Trinidad
Tejada, Maria-Isabel
Gonzalez-Neira, Anna
Benitez, Javier
Source :
American Journal of Human Genetics. Feb 13, 2009, Vol. 84 Issue 2, p115, 8 p.
Publication Year :
2009

Abstract

A SNP-based genome-wide linkage scan is conducted to identify the various genes that lead to breast cancer in families with cases not associated with BRCA1 or BRCA2 germline mutations. The phenotypic and geographic homogeneity are considered to be the most important factors that need to be considered while performing such studies.

Details

Language :
English
ISSN :
00029297
Volume :
84
Issue :
2
Database :
Gale General OneFile
Journal :
American Journal of Human Genetics
Publication Type :
Academic Journal
Accession number :
edsgcl.221456048