Common variation in the [beta]-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study

A genome-wide association study is conducted for the identification of the novel common variants that are associated with the circulating carotenoid levels and known lipid variants associated with [alpha]-tocopherol levels. The common variation taking place in the [beta]-carotene 15,15'-monooxygenase 1 gene is shown to affect the circulating levels of carotenoids.