Effects of carbon dioxide on growth of proteolytic Clostridium botulinum, its ability to produce neurotoxin, and its transcriptome

Authors :: Artin, Ingrid
Mason, David R.
Pin, Carmen
Schelin, Jenny
Peck, Michael W.
Holst, Elisabet
Radstrom, Peter
Carter, Andrew T.
Source :: Applied and Environmental Microbiology. Feb, 2010, Vol. 76 Issue 3-4, 1168-1172
Publication Year :: 2010
Abstract: The effects of C[O.sub.2] on gene expression and neurotoxin formation by proteolytic Clostridium botulinum type A1 strain ATCC 3502 are analyzed during the growth cycle. Microarray analysis has enabled the identification of coding sequences whose expression profiles have matched with those of the neurotoxin cluster and a DNA microarray is used for studying the transcriptome.

Subjects :: Bacterial toxins -- Research
Carbon dioxide -- Environmental aspects
Clostridium -- Genetic aspects
Clostridium -- Physiological aspects
Gene expression -- Analysis
Biological sciences

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