Targeted capture and next-generation sequencing identifies C9orf75, encoding taperin, as the mutated gene in nonsyndromic deafness DFNB79

A study uses targeted capture and next-generation sequencing to identify the gene which causes nonsyndromic deafness DFNB79. Results reveal that a nonsense mutation in the gene C9orf75, also called TPRN, which encodes the protein taperin, is responsible for the nonsyndromic deafness DFNB79.