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Dried blood spot real-time polymerase chain reaction assays to screen newborns for congenital cytomegalovirus infection

Authors :
Boppana, Suresh B.
Ross, Shannon A.
Novak, Zdenek
Masako Shimamura
Tolan, Robert W. Jr.
Palmer, April L.
Ahmed, Amina
Michaels, Marian G.
Sanchez, Pablo J.
Bernstein, David I.
Britt, William J.
Bowler, Karen B.
Source :
JAMA, The Journal of the American Medical Association. April 14, 2010, Vol. 303 Issue 14, p1375, 8 p.
Publication Year :
2010

Abstract

A study was conducted to evaluate the accuracy of dried blood spot (DBS) real-time polymerase chain reaction (PCR) assays in the screening of newborn infants with congenital cytomegalovirus (CMV) infection. Results indicated that the screening method had lower sensitivity and thus was limited in its scope.

Subjects

Subjects :
Polymerase chain reaction -- Usage
Cytomegalovirus infections -- Diagnosis
Cytomegalovirus infections -- Care and treatment
Infants (Newborn) -- Care and treatment
Medical screening -- Evaluation

Details

Language :
English
ISSN :
00987484
Volume :
303
Issue :
14
Database :
Gale General OneFile
Journal :
JAMA, The Journal of the American Medical Association
Publication Type :
Academic Journal
Accession number :
edsgcl.226331743

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