Six-component reactions for the stereoselective synthesis of 3-arylidene-2-oxindoles via sequential one-pot Ugi/Heck carbocyclization/Sonogashira/nucleophilic addition

Authors :: Bararjanian, Morteza
Balalaie, Saeed
Rominger, Frank
Movassagh, Barahman
Bijanzadeh, Hamid Reza
Source :: Journal of Organic Chemistry. May 7, 2010, Vol. 75 Issue 9, 2806-2812
Publication Year :: 2010
Abstract: An efficient palladium-catalyzed protocol was developed for the synthesis of 3-arylidene-2-oxindoles. The synthesis involved a sequential one-pot six-component reaction via Ugi/Heck carbocyclization/Sonogashira/nucleophilic addition to yield desired skeleton.

Subjects :: Aromatic compounds -- Chemical properties
Chemical synthesis -- Analysis
Palladium -- Chemical properties
Biological sciences
Chemistry

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