Real-time microsensor measurement of local metabolic activities in ex vivo dental biofilms exposed to sucrose and treated with chlorhexidine

A study was conducted to examine the metabolic activity like oxygen consumption and acid formation and viability and the effect of antimicrobial chlorhexidine (CHX) treatment on the physiology of the dental biofilms during exposure to sucrose. The CHX exposure was observed to reduce the metabolic activity and microbial viability at the biofilm surface and drove metabolic activity deeper into the biofilm.