Rapid release of entrapped contents from multi-functionalizable, surface cross-linked micelles upon different stimulation

The pyrene-containing water-soluble nanoparticle is under electrostatic stress when diluted below the CMC of the surfactant and extremely rapid release of the hydrophobic content is observed when the cross-linker is cleaved. The method has combined the ease of physical entrapment and the precision of chemical ligation and is useful in the delivery and controlled release of pharmaceutical agents.