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Genetic interception and structural characterization of thiopeptide cyclization precursors from Bacillus cereus
- Source :
- Journal of the American Chemical Society. Sept 8, 2010, Vol. 132 Issue 35, 12182-12184
- Publication Year :
- 2010
-
Abstract
- G enetic i nterception and s tructural c haracterization of t hiopeptide c yclization p recursors for thiocillins (tclM) from Bacillus cereus is described. The studies provide insight into the TclM and its homologues in other thiazolyl peptide producing strains as the enzymes reponsible for the trans-annular heteroannulation at core of this class of molecules.
Details
- Language :
- English
- ISSN :
- 00027863
- Volume :
- 132
- Issue :
- 35
- Database :
- Gale General OneFile
- Journal :
- Journal of the American Chemical Society
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.237413274