Maternal blood mitochondrial DNA content during normal and intrauterine growth restricted (IUGR) pregnancy

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ajog.2010.05.027 Byline: Francesca Colleoni (a), Debora Lattuada (b), Ambra Garretto (a)(c), Maddalena Massari (a), Chiara MandA[sup.2] (a), Edgardo Somigliana (b), Irene Cetin (a) Keywords: intrauterine growth restriction; maternal blood; mitochondrial DNA; pregnancy Abstract: We investigated mitochondrial DNA (mtDNA) content in the maternal circulation of normal pregnancies of different gestational ages and in pregnancies complicated by intrauterine growth restriction (IUGR). Author Affiliation: (a) Unit of Obstetrics and Gynecology, Department of Clinical Sciences 'L.Sacco' and Center for Fetal Research Giorgio Pardi, University of Milan, Milan, Italy (b) Department of Mother and Infant Sciences, University of Milan, Foundation Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy (c) Division of Obstetrics and Gynecology, San Paolo Hospital, Milan, Italy Article History: Received 11 March 2010; Revised 4 May 2010; Accepted 18 May 2010 Article Note: (footnote) Supported by the Sixth Framework Programme of the European Union (Pregenesys, Contract No. LSHB CT 2006 037244), Ministero della Salute (finalized project 'Role of new inflammatory molecules in pregnancy pathologies and in maternal-neonatal health') and by Associazione Italiana per lo Studio delle Malformazioni., Cite this article as: Colleoni F, Lattuada D, Garretto A, et al. Maternal blood mitochondrial DNA content during normal and intrauterine growth restricted (IUGR) pregnancy. Am J Obstet Gynecol 2010;203:365.e1-6.