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Conjugate addition of lithiated methyl pyridines to enones

Authors :
Taber, Douglass F.
Pengfei Guo
Pirnot, Michael T.
Source :
Journal of Organic Chemistry. August 20, 2010, Vol. 75 Issue 16, 5737-5739
Publication Year :
2010

Abstract

The conjugate addition of lithiated methyl pyridines to cyclic and acyclic enones is described. The addition of 2-picoline to 3-penten-2-one has led to a concise synthesis of the alkaloids ([plusmn])-senepodine G and ([plusmn])-cermizine C.

Details

Language :
English
ISSN :
00223263
Volume :
75
Issue :
16
Database :
Gale General OneFile
Journal :
Journal of Organic Chemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.238297303