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Functionalizable collagen model peptides

Authors :
Erdmann, Roman S.
Wennemers, Helma
Source :
Journal of the American Chemical Society. Oct 13, 2010, Vol. 132 Issue 40, 13957-13959
Publication Year :
2010

Abstract

The functionalizability and conformational properties of azidoproline (Azp)-containing collagen model peptides (CMPs) are analyzed. The results have shown that (4R)Azp has a similar stabilizing effect on the collagen triple helix as (4R)hydroxyproline and that functionalized CMPs are accessible by ' click' chemistry.

Subjects

Subjects :
Collagen -- Structure
Collagen -- Chemical properties
Hydroxyproline -- Chemical properties
Hydroxyproline -- Structure
Triazoles -- Structure
Triazoles -- Chemical properties
Chemistry

Details

Language :
English
ISSN :
00027863
Volume :
132
Issue :
40
Database :
Gale General OneFile
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
edsgcl.240543975

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