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Enzymatically triggered actuation of miniaturized tools

Authors :
Bassik, Noy
Brafman, Alla
Zarafshar, Aasiyeh M.
Jamal, Mustapha
Luvsanjav, Delgermaa
Selaru, Florin M.
Gracias, David H.
Source :
Journal of the American Chemical Society. Nov 24, 2010, Vol. 132 Issue 46, 16314-16317
Publication Year :
2010

Abstract

A method is described that has used the specificity of enzyme-substrate biomolecular interactions to trigger miniaturized tools under biocompatible conditions. The utility of the enzymatically triggered tools is highlighted by showing the biopsy of liver tissue from a model organ system and gripping and releasing an alginate bead.

Subjects

Subjects :
Enzyme binding -- Analysis
Ferromagnetism -- Analysis
Biomolecules -- Structure
Biomolecules -- Chemical properties
Liver cells -- Physiological aspects
Chemistry

Details

Language :
English
ISSN :
00027863
Volume :
132
Issue :
46
Database :
Gale General OneFile
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
edsgcl.244998358

Tools

Authors Abstract Subjects Details